Multi-biomarker risk stratification in heart failure: a story of diminished marginal returns after Herculean efforts?
نویسندگان
چکیده
منابع مشابه
Risk stratification in chronic heart failure.
Despite advances in medical and surgical management, the prognosis of chronic heart failure remains poor. Few patients with chronic heart failure can be considered to have a good prognosis, but different trials have indicated a 6 month mortality between 5% and 60% depending on the severity of heart failure; identifying patients at truly low risk is difficult. A host of factors have been identif...
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Background: As suggested by the Minorities’ Diminished Returns (MDRs) theory, educational attainment shows a weaker protective effect for racial and ethnic minority groups compared to non-Hispanic Whites. This pattern, however, is never shown for hospitalization risk. Objectives: This cross-sectional study explored racial and ethnic variations in the asso...
متن کاملUse of myeloperoxidase for risk stratification in acute heart failure.
BACKGROUND Myeloperoxidase (MPO) is a biomarker of inflammation and oxidative stress produced by neutrophils, monocytes, and endothelial cells. Concentrations of MPO predict mortality in patients with chronic heart failure. This study sought to investigate the diagnostic accuracy and prognostic value of MPO in patients with acute heart failure (AHF). METHODS We prospectively enrolled 667 pati...
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The emergency department evaluation and management of patients who have potential acute heart failure syndromes (AHFS) has remained a significant challenge for decades. The emergency physician's diagnostic tools for heart failure have remained limited, and the complexity of the syndrome itself has led to risk-averse practice styles with extremely high admission rates. Recently, new diagnostic m...
متن کاملHeart Failure Role of Brain Natriuretic Peptide in Risk Stratification of Patients With Congestive Heart Failure
OBJECTIVES Using a prospective study design, we assessed the value of brain natriuretic peptide (BNP) to identify patients with heart failure who have an increased risk of deterioration of their functional status. Furthermore, we examined the relationship between BNP and various clinical characteristics incorporated into an established survival model used for risk stratification. BACKGROUND Pre...
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ژورنال
عنوان ژورنال: European Journal of Heart Failure
سال: 2017
ISSN: 1388-9842
DOI: 10.1002/ejhf.1035